Why Longevity Starts with Rebooting Your Defenses

The most powerful anti-aging therapy might not be a gene hack, but restoring the immune conversations that keep us alive.

Update: Plasma proteomics links brain and immune system aging with healthspan and longevity.

Hallmarks of immunosenescence. Aging brings thymic involution (less new T‑cell production), chronic systemic inflammation (inflammaging), metabolic shifts in immune cells, and skewed blood-cell production. These changes collectively weaken host defense and promote age‑related disease.